VEGFR2-luc

(Vascular Endothelial Growth Factor Receptor-2)

Application to wound healing and burn injury:
Can be used to monitor vascular remodeling and angiogenesis.  Shown to be up-regulated following cutaneous wound injury with a peak ~7-10 days.

References (Selected applications):
1. Zhang N, Fang Z, Contag PR, Purchio AF, West D, Blood. 2004 Jan 15;103(2):617-26. Epub 2003 Sep 25.

Pubmed link (14512298)

Background Strain:  FVB/N

TRANSGENIC REPORTER MODELS

VEGFR2-luc

NF-kB-luc

Smad 2/3-luc

GFAP-luc

NFAT5-luc