Smad 2/3-luc
(Smad 2 and 3)
Application to wound healing and burn injury:
Can be used to monitor TGFb signaling and is a marker for scarring. Shown to be up-regulated following cutaneous wound injury with a peak 1-3 days.
References (Selected applications):
1. Lin AH, Luo J, Mondshein LH, ten Dijke P, Vivien D, Contag CH, Wyss-Coray T. J Immunol. 2005 Jul 1;175(1):547-54
Pubmed link (15972691)
Background Strain: FVB/N