NFAT5-luc

(Nuclear factor of activated T-cells 5, tonicity-responsive, NFAT5)

Application to wound healing and burn injury:
Can be used to monitor osmolarity.  Shown to be up-regulated following increased with a peak 24-72 hours.

References (Selected applications):
1. Morancho B, Minguillón J, Molkentin JD, López-Rodríguez C, Aramburu J., BMC Mol Biol. 2008 Jan 25;9:13.

Pubmed link (18221508)

Background Strain:  FVB/N

TRANSGENIC REPORTER MODELS

VEGFR2-luc

NF-kB-luc

Smad 2/3-luc

GFAP-luc

NFAT5-luc