Research

Research in the Baird lab is focused on the development and bioengineering of modified growth factors in synthetic matrices.  The application of combinatorial display enables the screening of peptide libraries and the genetic engineering of growth factors and gene delivery vehicles that regulate bioavailability in the wound bed.

Research in the Eliceiri lab is focused on the characterization of mechanisms regulating fluid balance, edema and re-epithelization following burn/acute injury.  Genetic modeling in mice cutaneous injury and intravital imaging of vascular remodeling constitute the core expertise in the development of re-engineered growth factors and related biotherapeutics.

Research in the Mueller lab is focused on the role of proteases in the regulation of re-epithelization in response to burn/injury.  The application of in vivo and in vitro models of senescence to examine remodeling of the extracellular matrix are examined in animals with mutations in specific proteases.